Search results for "Fluorescence loss in photobleaching"

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Dynamics and interactions of parvoviral NS1 protein in the nucleus

2007

Summary Nuclear positioning and dynamic interactions of viral proteins with nuclear substructures play essen- tial roles during infection with DNA viruses. Visual- ization of the intranuclear interactions and motility of the parvovirus replication protein (NS1) in living cells gives insight into specific parvovirus protein- cellular structure interactions. Confocal analysis of highly synchronized infected Norden Laboratory Feline Kidney cells showed accumulation of nuclear NS1 in discrete interchromosomal foci. NS1 fused with enhanced yellow fluorescence protein (NS1- EYFP) provided a marker in live cells for dynamics of NS1 traced by photobleaching techniques. Fluo- rescence Recovery after…

ConfocalvirusesImmunologyMotilityViral Nonstructural ProteinsBiologyVirus ReplicationMicrobiologyCell LineParvoviruschemistry.chemical_compoundBacterial ProteinsVirologymedicineAnimalsFluorescence loss in photobleachingCell NucleusPhotobleachingParvovirusvirus diseasesbiochemical phenomena metabolism and nutritionbiology.organism_classificationMolecular biologyFluorescencePhotobleachingCell biologyLuminescent Proteinsmedicine.anatomical_structurechemistryCatsNucleusDNACellular Microbiology

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PEPhysical Sciences and Engineering
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